T D Bradshaw Selected Research

Phortress

1/2009	Preclinical toxicokinetic evaluation of phortress [2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole lysylamide dihydrochloride] in two rodent species.
4/2004	The development of the antitumour benzothiazole prodrug, Phortress, as a clinical candidate.
2/2003	Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo.
1/2002	The aryl hydrocarbon receptor in anticancer drug discovery: friend or foe?

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

T D Bradshaw Research Topics

Disease

5	Neoplasms (Cancer) 11/2011 - 09/2000
5	Breast Neoplasms (Breast Cancer) 01/2005 - 07/2000
4	Carcinoma (Carcinomatosis) 11/2011 - 02/2001
1	Glioma (Gliomas) 11/2011
1	Inflammation (Inflammations) 11/2011
1	Necrosis 11/2011
1	Body Weight (Weight, Body) 01/2009
1	Hypoxia (Hypoxemia) 01/2005
1	Ovarian Neoplasms (Ovarian Cancer) 01/2004
1	Genomic Instability 01/2004
1	Carcinogenesis 01/2002

Drug/Important Bio-Agent (IBA)

4	PhortressIBA 01/2009 - 01/2002
3	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 01/2009 - 09/2000
3	NSC 674495IBA 04/2004 - 07/2000
3	2-(4-aminophenyl)benzothiazoleIBA 01/2002 - 07/2000
2	DNA (Deoxyribonucleic Acid)IBA 11/2011 - 01/2004
2	benzothiazoleIBA 01/2005 - 02/2001
2	BenzothiazolesIBA 04/2004 - 02/2001
2	Proteins (Proteins, Gene)FDA Link 02/2003 - 04/2002
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 02/2003 - 01/2002
1	PowdersIBA 11/2011
1	ethyl acetateIBA 11/2011
1	Ethanol (Ethyl Alcohol)IBA 11/2011
1	Eosine Yellowish-(YS) (Eosin)IBA 11/2011
1	HexanesIBA 11/2011
1	Plant ExtractsIBA 11/2011
1	beta-Galactosidase (Lactaid)IBA 01/2009
1	Alkaline PhosphataseIBA 01/2009
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2005
1	Thioredoxin-Disulfide ReductaseIBA 01/2005
1	Pharmaceutical PreparationsIBA 01/2005
1	ThioredoxinsIBA 01/2005
1	HydroquinonesIBA 01/2005
1	RNA (Ribonucleic Acid)IBA 01/2004
1	ProdrugsIBA 01/2002
1	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 01/2002
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2002
1	DNA AdductsIBA 01/2002
1	LigandsIBA 01/2002
1	Protein Isoforms (Isoforms)IBA 01/2002
1	EnzymesIBA 01/2002
1	Biological ProductsIBA 01/2002
1	XenobioticsIBA 01/2002